Problems such as sore throat or nausea may be caused by anesthesia. Even so, be sure to ask about insurance coverage before you decide to have the bone marrow harvest done. Once the cells are collected, they are filtered through fine mesh screens. This prevents bone or fat particles from being given to the recipient. For an allogeneic or syngeneic transplant, the cells may be given to the recipient through a vein soon after they are harvested. For several days before starting the donation process, the donor is given a daily injection shot of a drug that causes the bone marrow to make and release a lot of stem cells into the blood.
Filgrastim can cause some side effects, the most common being bone pain and headaches. These may be helped by over-the-counter pain medications or nonsteroidal anti-inflammatory drugs.
Nausea , sleeping problems , low-grade mild fevers, and tiredness are other possible effects. These go away once the injections are finished and collection is completed. The stem cells are kept while the rest of the blood is returned to the donor, often through the same catheter. In some cases, a catheter may be put in each arm — one takes out blood and the other puts it back. This process is called apheresis. It takes about 2 to 4 hours and is done as an outpatient procedure. Often the process needs to be repeated daily for a few days, until enough stem cells have been collected.
Possible side effects of the catheter can include trouble placing the catheter in the vein, blockage of the catheter, or infection of the catheter or at the area where it enters the vein.
Blood clots are another possible side effect. During the apheresis procedure, donors may have problems caused by low calcium levels from the anti-coagulant drug used to keep the blood from clotting in the machine. These can include feeling lightheaded or tingly, and having chills or muscle cramps. These go away after donation is complete, but may be treated by giving the donor calcium supplements.
The process of donating cells for yourself autologous stem cell donation is pretty much the same as when someone donates them for someone else allogeneic donation. After the bone marrow is collected, you'll be taken to the recovery room while the anesthetic wears off. You may then be taken to a hospital room where the nursing staff can monitor you. When you're fully alert and able to eat and drink, you'll likely be released from the hospital.
If blood stem cells are going to be collected directly from your blood, you'll be given injections of a medication to stimulate the production of blood stem cells so that more of them are circulating in your bloodstream. The medication is usually started several days before you're going to donate.
During the donation, blood is usually taken out through a catheter in a vein in your arm. The blood is sent through a machine that takes out the stem cells. The unused components are returned to your bloodstream. This process is called apheresis. It typically takes up to two hours and is done as an outpatient procedure.
You'll typically undergo two to four apheresis sessions, depending on how many blood stem cells are needed. Recovery times vary depending on the individual and type of donation. But most blood stem cell donors are able to return to their usual activities within a few days to a week after donation.
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This content does not have an Arabic version. Overview If you are planning to donate stem cells, you have agreed to allow doctors to draw bone marrow stem cells from either your blood or bone marrow for transplantation.
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Accessed May 7, Blood-forming stem cell transplants. National Cancer Institute. FAQs about joining. National Marrow Donor Program. Micromedex 2. HLA matching. What we do Our organisation Our history Our funding Our trustees Our stories Donor stories Patient stories Supporter stories Our influence The transplant pathway Our campaign successes Our research Our science explained How we fund our research Impact of our research Help save a life Patient Appeals Our current Appeals Get involved in an appeal Donate your stem cells Donate your umbilical cord Update your register contact details After your donation Donate money Leave a gift in your will Play our Weekly Lottery Where your money goes Fundraise with us Do your own fundraising Find a challenge event Run for charity Cycle for charity Volunteer with us Youth volunteering Short and sweet Get more involved Something more regular For patients and families Blood cancers and blood disorders What is blood cancer?
What is a blood disorder? Join the register. Contents Blood cancers and blood disorders What is blood cancer? Understanding stem cell transplants What is a stem cell transplant? Different types of stem cell transplant What is an autologous transplant? What is a cord blood transplant? What is a haploidentical transplant? What is a matched unrelated donor transplant?
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